Regular visitors to this blog will be familiar with recent continuous flow chemistry events in what I consider to be a very exciting, fast-developing area of chemistry. When I was reading the recent blog post regarding the upcoming Pfizer Flow Technology Expo, I thought about other upcoming flow chemistry events, including: Continue reading
At the recent 17th International Process Development Conference in Baltimore there was an excellent session discussing continuous flow chemistry. The desire to develop new and improved chemical processes that optimize the use of resources has facilitated a large amount of work in the development of Continuous Flow Reactor (CFR) technologies in recent years.
Modern flow reactors can deliver a number of distinct advantages over more traditional batch reactor technology. For example, reaction conditions that may be challenging to achieve in a batch reactor can be easier to achieve in a flow reactor. A good example is a reaction in which the temperature of the reaction far exceeds the boiling point of the solvent. This type of reaction can be easily run due to the flow reactor’s ability to contain pressure. (The ThalesNano’s H-Cube pictured above is a widely used CFR designed specifically to simplify screening and development of continuous hydrogenation reactions.) Continue reading