Tag Archives: size

Measuring Fines Precipitation to Improve Solid/Liquid Separations

Poor filtration and bulk density are often related to the number of fine particles present in a system. Inline particle size and count measurements identify the exact moment and conditions when fine particle formation occurs. By pinpointing the source of the inconsistency, the root cause can be identified, and a smarter process may be developed with improved solid/ liquid separations. Continue reading

Best Practice For Inline Particle Size Characterization

 Chemists, engineers, and biologists are often challenged by processes involving particle or droplet systems. Solid or liquid dispersion, homogenization, agglomeration, or precipitation can create variability in product stability and manufacturing throughput. To develop and manufacture world class products at competitive costs, scientists and engineers use inline particle size measurements to optimize process conditions and consistently meet product quality specifications, at the bench or in manufacturing. Continue reading

Advances For Seeding A Crystallization Process

Seeding has become one of the most critical steps in optimizing crystallization behavior, process efficiency, and product quality. Inconsistent filtration rates, drying times, yields, bulk density, flow properties, and particle size distributions can often be traced back to inconsistent seeding and nucleation. Many parameters must be taken into consideration when designing a seeding strategy such as seed size, seed loading (mass) and seed addition temperature. These parameters are generally optimized based on process kinetics and the desired final particle properties and must remain consistent during scale-up and technology transfer. Continue reading

Analysis of Particle Sizes in Process Workshop

The Analysis of Particle Sizes in Process: Measuring Techniques for Emulsions and Suspensions Workshop takes place this week (October 10-12) at the University of Potsdam Institute for Chemistry.  This workshop not only focuses the theory of particle size but also the technology that can be used for real-time, in-process measurements. One of the most interesting sessions will be on the emerging areas where particle size is gaining traction – particle measurement in biotechnology. Continue reading

HANBAT International Workshop on Industrial and Pharmaceutical Crystallization

Crystallization is a complicated process where the final crystal product is a function of thermodynamics as well as kinetic and physical phenomenon. Continue reading

19th International Workshop on Industrial Crystallization – BIWIC 2012

During BIWIC 2012 (19th International Workshop on Industrial Crystallization) in China, I will present a poster – Amalgamated Sugar Experiences with Inline Particle Size, Shape, and Count Characterization:  Real-Time Crystal Nucleation and Growth Rates in an Industrial Semi-batch Crystallizer. Continue reading

Engineering Fine Particle Size Distributions with Inline Particle Size Measurements

Crystal engineering is applied when the crystal size distribution is too large to meet downstream specifications. By designing the crystallization to produce a fine crystal distribution in situ, downstream milling operations are avoided, thus improving the yield, and reducing energy consumption or safety hazards which may arise due to milling. Continue reading

Improve Oil-Water Droplet Separation to Optimize Oil Recovery

At the 2011 PetroPhase 12 conference in London, we presented a poster showing how inline droplet size measurement is applied to optimize liquid-liquid separations. Continue reading

Petrophase 13 – Optimize Particle-Water-Oil Separations in Dark Crude Oil

The 13th International Conference on Petroleum Phase Behavior and Fouling will be held June 10 – 14, 2012 in St. Petersburg Beach, Florida. Continue reading

Robust Crystallization Processes Developed With Workstations

httpv://www.youtube.com/watch?v=vc6lEepLb-4
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