Tag Archives: sieving

PSAIChE Biotech: Optimize Flocculation With Real Time Particle Characterization

Since the Seattle area is well known for biotech, I was not surprised when the November Puget Sound American Institute of Chemical Engineers (AIChE) meeting focused on the cell fermentation process at Amgen.   The AIChE meeting featured the presentation by Amgen’s Anna Senczuk:  Continue reading

Online Monitoring Particle Milling – EMS and IIPF

I recently had the pleasure of collaborating with a group of very talented scientists at EMS and International Institute of Pharmaceutical Research (IIPF).  EMS and IIPF are two pharmaceutical companies based in Hortolândia, a city roughly 100 miles northwest of Sao Paulo, Brazil. We worked on an interesting project where FBRM was used to track Active Pharmaceutical Ingredient (API) particle size reduction during wet milling. Traditionally, offline laser diffraction had been used to track this process; however this approach proved to be time consuming, prone to inaccuracy and potentially hazardous. Continue reading