Tag Archives: round bottom flasks

Synthetic Chemistry Beyond The Round Bottom Flask

While analytical technologies that support synthetic organic chemistry in the laboratory have changed dramatically, chemical synthesis itself has remained largely unchanged for over fifty years.  During that time, the round bottom flask has been the workhorse for organic chemists in the synthesis lab. Continue reading

How to Use a Crystallization Workstation to Optimize Space for Process Understanding

During crystallization development, chemists often produce crystals rapidly without time for a full Design of Experiment (DoE).  Continue reading

4 Ways To Improve Organic Synthesis

In collaboration with Pfizer, I will make a presentation on Four Ways To Improve Organic Synthesis on July 20, 2011. Continue reading

The Three Little Chemists: A Story About Tr-Tj

Three Little Pigs Tr Tj StoryFor years, we have been discussing the value of the Tr-Tj expression (Tr = reaction temperature, Tj = heating/cooling jacket temperature). The ease of use and the valuable insight gained into chemistry from the Tr-Tj expression has already been leveraged by chemists around the world. Since I feel that there are more chemists out there who would benefit from the use of Tr-Tj on a regular basis, I thought I would tell a story to illustrate the value of the Tr-Tj expression. Continue reading