Tag Archives: process

Reaction Calorimetry For Safe Process Scale-up

Reaction calorimetry provides information quickly which can be applied to quantify the risks and criticality associated with a chemical process. Reaction calorimetry helps identify key process parameters, including: Continue reading

AIChE 2013 Spring Meeting and 9th Global Congress on Process Safety

I would like to thank the American Institute of Chemical Engineers (AIChE) and William Hollar (Sabic) for inviting METTLER TOLEDO to present a paper at AIChE Spring 2013 Session in San Antonio last week. The session –  New Approaches in Chemical Manufacturing Operations – Continue reading

Process Development Event – Durham, NC

On May 14, my colleagues and I will host an Information Sharing Event at the Marriott Hotel at Research Triangle Park.  This is a free event intended for scientists interested in learning about applications for chemical process development.  We have six speakers from industry and academia for this event: Continue reading

Best Practice For Inline Particle Size Characterization

 Chemists, engineers, and biologists are often challenged by processes involving particle or droplet systems. Solid or liquid dispersion, homogenization, agglomeration, or precipitation can create variability in product stability and manufacturing throughput. To develop and manufacture world class products at competitive costs, scientists and engineers use inline particle size measurements to optimize process conditions and consistently meet product quality specifications, at the bench or in manufacturing. Continue reading

Advances For Seeding A Crystallization Process

Seeding has become one of the most critical steps in optimizing crystallization behavior, process efficiency, and product quality. Inconsistent filtration rates, drying times, yields, bulk density, flow properties, and particle size distributions can often be traced back to inconsistent seeding and nucleation. Many parameters must be taken into consideration when designing a seeding strategy such as seed size, seed loading (mass) and seed addition temperature. These parameters are generally optimized based on process kinetics and the desired final particle properties and must remain consistent during scale-up and technology transfer. Continue reading

Analysis of Particle Sizes in Process Workshop

The Analysis of Particle Sizes in Process: Measuring Techniques for Emulsions and Suspensions Workshop takes place this week (October 10-12) at the University of Potsdam Institute for Chemistry.  This workshop not only focuses the theory of particle size but also the technology that can be used for real-time, in-process measurements. One of the most interesting sessions will be on the emerging areas where particle size is gaining traction – particle measurement in biotechnology. Continue reading

Mary Kay O’Connor Process Safety Center Conference

In conjunction with the Mary Kay O’Connor Process Safety Center, a Process Scale-up, Process Safety, Hazards Evaluation, Mass Transfer and Mixing Challenges Conference will be held on August 14 and 15 at Texas A&M University.  Conference topics include: Continue reading