Tag Archives: Process Development and Scale-up

Process Development at AIChE 2010

While reviewing the agenda for next month’s American Institute of Chemical Engineers (AIChE) Annual Meeting, I noticed a number of papers and posters discussing process development in pharmaceuticals, chemicals, and academia: Continue reading

Optimize Chemistry Via Kinetic Analysis

On October 20, Professor Donna Blackmond will present the second part of a webinar series – Reaction Progress Kinetic Analysis: A Powerful Methodology for Streamlining the Study of Complex Organic Reactions. Continue reading

How Pfizer Is Improving Process Development For Bench Scientists

Recently, Dr. Marty Guinn, Director of Chemical Development for Pharma Therapeutics at Pfizer, wrote: Continue reading

AIChE 2010 – Analytical and Optimization Tools in Pilot Plants Session

Among the presentations in the Advanced On-Line Analytical and Optimization Tools in Pilots Plants Session at the 2010 American Institute of Chemical Engineers (AIChE) Annual Meeting will be the New Developments in Heat Transfer Scale Down and In Situ FT-IR Scale-up From the Lab to the Plant.  The presentation, which will be given by Leen Schellekens, will include the challenges that Chemical Engineers face in the chemical and pharmaceutical industries, including globalization, environmental and safety regulations, and shortening product life cycles and the ever increasing time pressure for commercial releases.
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Congratulations to 17th IPDC Award Winners: Best Paper Award presented to Dr. Martin Johnson of Eli Lilly

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Martin Johnson, Eli Lilly

METTLER TOLEDO is pleased to announce that Dr. Martin D. Johnson of Eli Lilly won the award for Best Paper at the 17th International Process Development Conference (IPDC).

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The Future of Chemical Research and Development: The Demise of the Round Bottomed Flask

ISPE-New-England-Chapter-BioPharma-ConferenceLast Thursday, May 6th, I attended the ISPE (International Society for Pharmaceutical Engineering) New England Chapter Biopharma 2010 Conference held in Warwick, Rhode Island.  A presentation was given by Geraldine Taber, Pfizer’s Global Technology Group Leader titled “Demise of the Round-Bottomed Flask – How new Battle Tools in the Lab of the Future are delivering value for R&D”.

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Reducing Time to Manufacturing Using Real-time In Situ FTIR Analytics as a Process Analytical Technology (PAT) Tool – On-Demand Webinar

The on-demand version of the Reducing Time to Manufacturing Using Real-time In Situ FTIR Analytics as a Process Analytical Technology (PAT) Tool webinar that I presented on January 20 is now available.

View the Reducing Time to Manufacturing On-Demand Webinar.

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During this on-demand webinar, I review case studies from the pharmaceutical industry to show how real-time mid-infrared (mid-IR) analytics provide critical information that results in shorter process development timelines, including:

  • Intermediate detection during an indazole alkylation and scale-up – Pfizer
  • Hazardous gas detection during tetrazole synthesis – Merck
  • Monitoring a Grignard reaction at the multikilogram scale – Bristol-Myers Squibb
  • Scale-up involving a sensitive enolate – Johnson and Johnson (J&J)

If you have any questions or would like to discuss this further, then please contact me.

17th International Process Development Conference – registration is open

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The 17th International Process Development Conference will be held in Baltimore, Maryland, USA from May 16-19, 2010.

The International Process Development Conference (IPDC) is an annual meeting, hosted by METTLER TOLEDO, which brings together industrial and academic researchers focused on chemical and pharmaceutical process research, scale-up, and manufacturing.

Past conferences have received extremely high marks for the value of the information shared by industry and the quality networking opportunities. Registration discounts are available for university researchers and for users of METTLER TOLEDO automated lab reactors and process analytical technologies.

Conference agenda will include sessions on:

  • Chemical Process Research
  • Crystallization
  • Process Safety & Process Scale-up
  • Process Analytical Technology (PAT) and Quality by Design (QbD)
  • Continuous Processing
  • Emerging Research with Controlled Reactors and Process Analytics
  • For more information

    Registration form