Tag Archives: Patheon Pharmaceuticals

Roller Compaction Process Optimization Using At Line Particle Characterization

roller-compaction-dry-granulation-FBRM-C35-METTLER-TOLEDO

METTLER TOLEDO C35 FBRM probe monitors roller compaction in real time

A successful process based on roller compaction followed by milling should produce a granule with consistent particle size distribution, density, and porosity control. Inconsistencies often occur during granulation scale-up due to changing raw materials or changing process dynamics.
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