Tag Archives: PAT tools

2010 AAPS Annual Meeting – Highlights

American Association of Pharmaceutical Scientists (AAPS) MeetingThis week, I was in New Orleans attending the 2010 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting. The AAPS Meeting combines a large trade show with technical presentation and poster sessions running in parallel.

At the 2010 AAPS meeting, hot topics included Quality by Design (QbD), Process Analytical Technology (PAT) and the drive towards real-time release for pharmaceutical products. FBRM and PVM technologies were well represented with numerous posters and presentations focusing on their use to understand, optimize and control particle size distribution during drug product formulation. Continue reading

How To Track Particle Distribution in Real Time: AAPS 2010

The 2010 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting will be held November 14 to 18 in New Orleans.  As thousands of pharmaceutical scientists from around the world prepare to gather for the AAPS conference that is being held in conjunction with the International Pharmaceutical Federation’s (FIP) Pharmaceutical Sciences World Congress (PSWC), I wanted to highlight some papers that will discuss how to track particle distribution in real-time:

Continue reading

AIChE 2010 – Quality by Design (QbD) Session

One presentation that will be given at the Quality by Design Session at the 2010 American Institute of Chemical Engineers (AIChE) Annual Meeting will be: Optimizing and Controlling High Value Processes Using the Principles of Quality by Design (QbD) Advanced Tools Such as Real-Time In Situ Particle Characterization, In Situ Mid-Infrared Spectrometry and Reaction Calorimetry.
Continue reading

Process Analytical Technology (PAT) Post Round-up

As there has been quite a bit of interest in Process Analytical Technology (PAT) by the readers of this blog, here are some interesting recent posts regarding this important topic:
Continue reading

Early Phase Implementation of Process Analytical Technology (PAT) Tools in Chemical Development

In the pharmaceutical industry, the pressure to decrease development times for new chemical entities is common.  During the recent 17th International Process Development Conference, Terry Connelly of Pfizer discussed this particular challenge during the presentation “Examples of Early Phase Implementation of Process Analytical Technology (PAT) Tools:  Meeting Short Term Goals While Setting the Stage for Long-Term Process Understanding and Control”.
Continue reading