While analytical technologies that support synthetic organic chemistry in the laboratory have changed dramatically, chemical synthesis itself has remained largely unchanged for over fifty years. During that time, the round bottom flask has been the workhorse for organic chemists in the synthesis lab. Continue reading
Basel, Switzerland is a unique place with an impressive concentration of scientists and engineers focused on optimizing pharmaceutical and fine chemical processes. Continue reading
After writing last week regarding recent advances to improve chemical development in the pharmaceutical industry, there were a lot of discussions about the top 4 ways to improve organic synthesis. Continue reading
In the pharmaceutical industry today, several challenges exist in chemical development, including: Continue reading
Traditional offline methods to analyze reaction chemistry, such as High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR) Spectroscopy, and Gas Chromatography (GC), share a common problem: when a sample is removed for analysis, it may be altered or compromised resulting in significant analytical errors. The solution for this is Continue reading
During the 2010 Fall American Chemical Society (ACS) meeting in Boston, Professor Steven V. Ley presented a novel approach to the use of flow chemistry as a synthetic technique. Continue reading
Paul Scholl will present a free online seminar – Recent Advances in Organic Chemistry in Academia Using Real-Time In Situ FTIR – on July 28. This on-going series reviews recent advances in organic chemistry by academia where real-time in situ mid-infrared (mid-IR) analytics played a role in the advancement of organic chemistry research.
During the Recent Advances in Organic Chemistry seminar, Paul will discuss several recent publications by academia illustrating how real-time in situ Fourier Transform Infrared spectroscopy (FTIR) was used to help advance the fundamental understanding of organic chemistry. During this series, the following research areas have been discussed: