Tag Archives: metastable zone width

Supersaturation: Driving Force For Crystal Nucleation & Growth

This is the third blog post in a series dedicated to crystallization.  In case you missed the first and second in the series, they are available here: Introduction to Crystallization and Precipitation and Common Ways to Reduce Solubility and Drive Crystallization.

Supersaturation is the driving force for all solution crystallization processes. Crystallization scientists gain control over crystallization process and product quality by carefully controlling the prevailing level of supersaturation during the process. Continue reading

Automating Crystallization Development

On Wednesday, I presented an online seminar: Automating Crystallization Development: Metastable Zone Width Determination and Supersaturation Control, which summarized a two day collaboration with a major pharmaceutical company where crystallization development time was reduced and scale-up efficiency was improved. Continue reading