Tag Archives: metal carbenoid chemistry

Understanding Asymmetric Rhodium Catalyzed Carbenoid Reactions

As you may recall, my colleague, Dominique Hebrault, referenced the research of Professor Huw M.L. Davies and his colleagues at Emory University in a presentation that discussed  Continue reading

Is Lithium Salt More Like Organolithium Or Azaenolate?

2-Lithio-3,3-dimethyl-2-oxazolinyloxirane: Carbanion or Azaenolate?

Vito Capriati*, Saverio Florio*, Renzo Luisi, Filippo Maria Perna and Agnese Spina
Dipartimento Farmaco-Chimico, Università di Bari, Consorzio Interuniversitario Nazionale Metodologie e Processi Innovativi di Sintesi C.I.N.M.P.I.S., Via E. Orabona 4, I-70125 Bari, Italy; J. Org. Chem., 2008, 73 (24), pp 9552–9564.

Structure, Configurational Stability and Stereodynamics in Solution
During this work, Vito Capriati, Saverio Florio and colleagues at the University of Bari in Italy used in situ Infrared (IR) and Nuclear Magnetic Resonance (NMR) spectroscopy together to give a better insight into the stability of lithium salt and to ultimately answer the question:

“Is the lithium salt more like an organolithium or is it more like an azaenolate?”
Continue reading

Heterobimetallic Bi−Rh Paddlewheel Carboxylates as Catalysts for Metal Carbenoid Transformations

Jørn Hansen†, Bo Li‡, Evgeny Dikarev‡, Jochen Autschbach§ and Huw M. L. Davies*†
† Department of Chemistry, Emory University, 440 Atwood Hall, 1515 Dickey Drive, Atlanta, Georgia 30322 ‡ Department of Chemistry, University at Albany, State University of New York, Albany, New York 12222 § Department of Chemistry, University at Buffalo, State University of New York, Buffalo, New York 14260-3000 J. Org. Chem., 2009, 74 (17), pp 6564–6571

Combined Experimental and Computational Studies
This paper reports on work by Huw Davies and colleagues at Emory University in Atlanta, GA. During their work, Professor Davies and his colleagues evaluate the catalytic activity of heterobimetallic Bi-Rh carboxylate complexes in metal carbenoid chemistry and cyclopropanation reactions. Continue reading

Recent Advances in Organic Chemistry by Academia Using Real-Time In Situ FTIR (fourier transform infrared spectroscopy) Online Seminar

Organic-Chemistry-Academia-Webinar-METTLER-TOLEDO

Recent Advances in Organic Chemistry by Academia

As part of the on-going Recent Advances in Organic Chemistry by Academia Using Real-Time In Situ FTIR online seminar series, Dominique Hebrault will review recent advances in organic chemistry where real-time mid-infrared (mid-IR) analytics played a role in the advancement of organic chemistry research.  This will take place on Wednesday, March 10.

Research topics include:

  • Advances in metal-catalyzed chemical transformations
    • Heterobimetallic for metal carbenoid chemistry as described by Huw M.L. Davies and colleagues at Emory University (United States)
    • Organolithium transformation from Vito Capriati, Saverio Florio, and colleagues from the University of Bari (Italy)
    • Palladium-catalyzed cross-coupling reactions as reported by Aiwen Lei and colleagues at Peking University (China)
    • Ruthenium-catalyzed dynamic kinetic resolution as described by Jan-E. Backvall and colleagues at Stockholm University (Sweden)
  • Highly selective polymerization reactions from Donald J. Darensbourg and colleagues at Texas A&M University (United States)
  • Chemical reactions in supercritical CO2 and system characterization from Paul A. Charpentier and colleagues at University of Western Ontario

Visit the Recent Advances in Organic Chemistry by Academia Using Real-Time In Situ FTIR online seminar page for more information.