Some of the major challenges faced by researchers (and in particular – organic and analytical chemists) include the need to quickly determine reaction kinetics as well as gain sufficient information to fully understand, characterize and optimize chemical reactions. This is leading researchers to find innovative ways to obtain the information they require to successfully complete their work.
I am happy to announce that the 18th International Process Development Conference (IPDC) will be held September 25 to September 29, 2011 in Weggis, Switzerland. This year’s conference will focus on workflows from compound development to manufacturing in the pharmaceutical, fine and specialty chemical industries: Continue reading
While reviewing the agenda for next month’s American Institute of Chemical Engineers (AIChE) Annual Meeting, I noticed a number of papers and posters discussing process development in pharmaceuticals, chemicals, and academia: Continue reading
On October 20, Professor Donna Blackmond will present the second part of a webinar series – Reaction Progress Kinetic Analysis: A Powerful Methodology for Streamlining the Study of Complex Organic Reactions. Continue reading
Arguably, kinetics is one of the least popular subjects in academic or industrial research. During her recent webinar – Reaction Progress Kinetic Analysis: A Powerful Methodology for Streamlining the Study of Complex Organic Reactions, Donna Blackmond reiterated why having kinetic data can be valuable:
Various physical and chemical processes interact during a manufacturing or synthesis process in a stirred tank reactor, including:
- Heat Transfer
- Thermodynamics; Equilibrium
- Mass transfer between phases
- Mixing to disperse multiple phases
- Physical property changes
Paul Scholl will present a free online seminar – Recent Advances in Organic Chemistry in Academia Using Real-Time In Situ FTIR – on July 28. This on-going series reviews recent advances in organic chemistry by academia where real-time in situ mid-infrared (mid-IR) analytics played a role in the advancement of organic chemistry research.
During the Recent Advances in Organic Chemistry seminar, Paul will discuss several recent publications by academia illustrating how real-time in situ Fourier Transform Infrared spectroscopy (FTIR) was used to help advance the fundamental understanding of organic chemistry. During this series, the following research areas have been discussed:
For a more detailed look at RPKA, check out this Free On-Demand Webinar (presented by Prof. Donna Blackmond): Reaction Progress Kinetic Analysis: A Powerful Methodology for Streamlining the Study of Complex Organic Reactions.
The Reaction Progress Kinetic Analysis (RPKA) Methodology, pioneered by Prof. Donna G. Blackmond of The Scripps Research Institute, requires far fewer reaction progress experiments than the classic kinetics approach. It accomplishes this by exploiting the extensive data available from accurate in-situ reaction monitoring under synthetically relevant conditions. The process is further streamlined by iC Kinetics software that automates the math and provides powerful visualizations to guide scientists to an understanding of reaction mechanisms and the selection of optimal reaction conditions.