Tag Archives: High Shear Granulation

YouTube Video: PowTech/TechnoPharm 2010 Innovation Award for METTLER TOLEDO FBRM C35

Earlier I posted that the METTLER TOLEDO Particle System Characterization group won an Innovation Award at the PowTech/TechnoPharm 2010 Exhibition for their FBRM C35 product for real-time monitoring of high-shear granulation and other challenging particulate processes.

In this video, Carl Phillip, Business Area Manager for Particle System Characterization, gives a short interview explaining why they earned the Innovation Award:

httpv://www.youtube.com/watch?v=O0y1CvWFMig

METTLER TOLEDO receives POWTECH award for Top Innovation in Particle Characterization and Material Sciences

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Dr. Markus Adamczyk, representing METTLER TOLEDO, accepts the award for top innovation in particle characterization and material science from Frank Jablonski and Gerd Kielburger

A couple of weeks ago, I posted an article about my colleagues’ attendance at POWTECH in Nuremberg. I was recently informed that while in Nuremberg, they accepted an award for this year’s most outstanding innovation in the field of Particle Characterization and Material Science at POWTECH. I thought I would share some of the details with you:
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In Process Particle Forum: Liquid and Solid Dosage Formulations

I am excited to be chairing the upcoming In Process Particle Forum focused on Liquid and Solid Dosage Formulations on September 15 in Woodbridge, NJ. This will be the third year in a row that METTLER TOLEDO has brought together expert users of FBRM and PVM to present their cutting edge research to a group of their peers. This year, we have the best agenda yet with four industry papers from:

  • Bristol-Myers Squibb
  • Merck
  • Johnson and Johnson
  • GlaxoSmithKline

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Optimization and Scale-up of High Shear Wet Granulation Processes

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FBRM® C35 with mechanical wiper for in situ granulation measurement

One goal of high shear granulation is to yield repeatable endpoint granule size, shape, and density distributions. This is necessary for consistent downstream flow properties, tablet consistency, and content uniformity. Quality by Design (QbD) is a concept applied to gain true process understanding through tools such as Design of Experiment (DoE), risk management, and Process Analytical Technology (PAT).

This extended abstract summarizes collaborative research between GlaxoSmithKline (GSK) and METTLER TOLEDO in the application of process analytical technologies (PAT) to the monitoring, optimization and control of High Shear Wet Granulation.

Download the extended abstract for this upcoming conference presentation.

Authors:
Zane Arp, GSK
Eric Dycus, Ben Smith, METTLER TOLEDO
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