Tag Archives: grignard

Optimization of Highly Reactive Chemistry – Reducing Risks

Highly reactive chemistry is the generic term referring to chemical reactions that pose a challenge due to the potentially hazardous and/or energetic nature of the reactants, intermediates and products that are present during synthesis. Highly reactive chemistries include Grignard, acid chloride, azide, halogenation, and hydrogenation.  Continue reading

Symposium on Green Processing in the Pharmaceutical & Fine Chemical Industries

Last week, John Tedesco and I had the privilege to attend the 3rd International Symposium on Green Processing in the Pharmaceutical & Fine Chemical Industries in Boston, MA. Continue reading

How To Optimize A Highly Reactive Chemistry

Highly Reactive Chemistry

Highly Reactive Chemistry

Highly reactive chemistries are used in the syntheses of drug molecules, special polymer products, herbicides and other agriculture products, high energy materials, and even special materials like nano-particles and chemo-sensors.

Examples of highly reactive chemistries include:

  • Azide chemistry
  • Diazo chemistry
  • Grignard chemistry
  • Lithium chemistry
  • Phosgene chemistry

Continue reading