Tag Archives: Fluid Bed Granulation

Predicting Dissolution Quality With Fluid Bed Granulation

Last month, Steve Mehrman of Johnson & Johnson gave a presentation on using Fluid Bed Granulation as a predictor of dissolution performanceContinue reading

Predictor of Dissolution Performance in Fluid Bed Granulation

In July, I announced that I would be chairing next week’s In Process Particle Forum  being held in Iselin, NJ.  Today, I want to highlight one of the papers that will be presented at In Process Particle ForumSteve Mehrman of Johnson & Johnson will present on using FBRM C35 during fluid bed granulation development and scale-up.

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Optimization and Scale-up of Fluid Bed Processes

Fluid Bed Granulation and Coating from GEA and Niro Pharma SystemsSpray layering is increasingly being used to produce spherical pellets of a target particle distribution – often with engineered dissolution profiles for time-release formulations.

This extended abstract summarizes collaborative research between GEA (Niro) Pharma Systems and METTLER TOLEDO in the application of process analytical technologies (PAT) to the monitoring, optimization and control of Precision Fluid Bed Granulation and Fluid Bed Coating.

Download the extended abstract from the presentation given at the 7th World Meeting on Pharmaceutics, Biopharmaceutics, and Pharmaceutical Technology.

Authors:
Andrew Birkmire, Dr. Kim Walters, GEA (Niro) Pharma
Dr. Mario Hubert, BMS
Eric Dycus, Terry Redman, Ben Smith, METTLER TOLEDO
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In Process Particle Forum: Liquid and Solid Dosage Formulations

I am excited to be chairing the upcoming In Process Particle Forum focused on Liquid and Solid Dosage Formulations on September 15 in Woodbridge, NJ. This will be the third year in a row that METTLER TOLEDO has brought together expert users of FBRM and PVM to present their cutting edge research to a group of their peers. This year, we have the best agenda yet with four industry papers from:

  • Bristol-Myers Squibb
  • Merck
  • Johnson and Johnson
  • GlaxoSmithKline

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