Tag Archives: flow chemistry

Continuous Flow Chemistry & Crystallization Development Symposium

In pharmaceutical development, the drive for better drug product quality, process reliability, efficiency and safety have become key factors in driving chemists and engineers to seek alternative methodologies. Continuous flow reactor technologies significantly expand the range and scope of possible chemistries, and allow for rapid testing, optimization, and scaling of chemical sequences. This is reflected in the dramatic increase in the variety and depth of published chemistry over the last few years. Continue reading

Use a Continuous Flow Reactor to Monitor Product Streams & Dispersion Effects

A flow chemistry system in combination with solid-supported reagents and scavengers was used to perform fluorination reactions in a continuous mode.   Using an inline analysis method, the effect of the solid supported reagents and scavengers on the product stream can be investigated.  Continue reading

Flow Chemistry – What’s Happening?

The desire to gain major improvements in product quality, yield, synthetic route, cycle time and safety in chemical processes have become key driving factors for chemists and engineers working in the chemical development and manufacturing environment in the pharmaceutical and fine chemical industries. In order to achieve these goals, scientists are actively seeking alternative chemical development methods such as modern continuous flow reactor technologies. These technologies provide the opportunity to address many of these issues as they allow for rapid testing, optimization, and scaling of chemical sequences, many of which are unsafe for batch operations.

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American Chemical Society (ACS) Flow Chemistry Resources

As I mentioned prior to the 241st American Chemical Society (ACS) National Meeting and Exposition in Anaheim, there was an Enabling and Optimizing Chemical Reactions in Real Time Flow Chemistry and In Situ Analysis workshop.  Continue reading

Upcoming Continuous Flow Chemistry Events

Regular visitors to this blog will be familiar with recent continuous flow chemistry events in what I consider to be a very exciting, fast-developing area of chemistry. When I was reading the recent blog post regarding the upcoming Pfizer Flow Technology Expo, I thought about other upcoming flow chemistry events, including: Continue reading

What is Continuous Flow Chemistry?

httpv://www.youtube.com/watch?v=A7Gb7sF4sjk

Continuous flow chemistry is widely used in the chemical and petrochemical markets, and has been for decades.  The continuous flow chemistry production methodology has been gaining interest in pharmaceutical R&D due to: Continue reading

Process Development Conference, Weggis, Switzerland

I am happy to announce that the 18th International Process Development Conference (IPDC) will be held September 25 to September 29, 2011 in Weggis, Switzerland.  This year’s conference will focus on workflows from compound development to manufacturing in the pharmaceutical, fine and specialty chemical industries: Continue reading