This is the sixth blog post in a special series dedicated to crystallization. In case you missed the previous posts in the series, they are available here:
- Introduction to Crystallization and Precipitation
- Common Ways to Reduce Solubility and Drive Crystallization
- Supersaturation: Driving Force For Crystal Nucleation & Growth
- Importance of Crystal Size and Shape Distribution
- Impact of Process Parameters on Supersaturation and Crystal Size and Shape
Previously, we looked at a case study that neatly illustrated the concept that slow supersaturation generation often results in a growth dominated process that is typically repeatable. As a rule of thumb, slow cooling works great – but its main drawback is the extended cycle times that often result. To overcome this problem, a common technique often used is non-linear cooling.
If we dive a little bit deeper into the governing equations of crystal growth and nucleation.. Continue reading