Category Archives: EasyMax

Synthetic Chemistry Beyond The Round Bottom Flask

While analytical technologies that support synthetic organic chemistry in the laboratory have changed dramatically, chemical synthesis itself has remained largely unchanged for over fifty years.  During that time, the round bottom flask has been the workhorse for organic chemists in the synthesis lab. Continue reading

4 Ways To Improve Organic Synthesis

In collaboration with Pfizer, I will make a presentation on Four Ways To Improve Organic Synthesis on July 20, 2011. Continue reading

Enhance Your Understanding of a Crystallization Process

A common challenge faced by both chemists and engineers is how to achieve an enhanced understanding of the crystallization process.

The EasyMax has provided a powerful, yet nimble platform for chemists and engineers to get a lot of work done.  It has been great to see how well the EasyMax has been embraced, especially for crystallization work.  Simon Rea developed a way to make it even better for particle characterization:

Crystallization Process FBRM PVM EasyMax

At last, you can use the FBRM and PVM simultaneously in your EasyMax!  This new PTFE lid makes it possible to see your: Continue reading

Methods For Teaching Chemical Kinetic Experiments

Some of the major challenges faced by researchers (and in particular – organic and analytical chemists) include the need to quickly determine reaction kinetics as well as gain sufficient information to fully understand, characterize and optimize chemical reactions.  This is leading researchers to find innovative ways to obtain the information they require to successfully complete their work.

Continue reading

Symposium on Process Safety and Crystallization

On Tuesday, November 2, METTLER TOLEDO held its 1st Symposium in Cambridge, MA, hosted by Novartis Institutes for BioMedical Research (NIBR). The success of the Symposium went beyond expectations: 65 scientists representing a large variety of small companies (CoNCERT, Cubist, Tetraphase), larger companies (Pfizer, Dow, Amgen), and research institutions (Massachusetts Institute of Technology) attended the event. The main themes of the Symposium were crystallization and process safety. Des O’Grady and I started by giving an overview of the technologies later covered by the industry speakers: Focused Beam Reflectance Measurement (FBRM®), Particle Video Microscope (PVM®), EasyMax™, RC1, and ReactIR™. Continue reading

How To Optimize Peptide Synthesis

This is the second blog post in a 2 part series where I discuss the real-time monitoring of bio-based chemical synthesis. Continue reading

Chemical Process Development Symposium at Novartis

Cambridge, Massachusetts is a unique place due to having one of the largest (per capita) and most impressive populations of scientists and engineers in the world.  Because of this, Cambridge is recognized as a global hub for biotechnology.  This makes the Boston area an attractive venue to organize a chemical process development gathering. Continue reading