Category Archives: PAT and QbD

Process Analytical Technology and Quality by Design

R&D and Manufacturing for Polymers, Fuels and Chemicals

Our latest R&D and Manufacturing for Polymers, Fuels and Chemicals Symposium in Houston on July 24 was a success.  The event featured well recognized experts, including: Continue reading

AIChE 2013 Spring Meeting and 9th Global Congress on Process Safety

I would like to thank the American Institute of Chemical Engineers (AIChE) and William Hollar (Sabic) for inviting METTLER TOLEDO to present a paper at AIChE Spring 2013 Session in San Antonio last week. The session –  New Approaches in Chemical Manufacturing Operations – Continue reading

Best Practice For Inline Particle Size Characterization

 Chemists, engineers, and biologists are often challenged by processes involving particle or droplet systems. Solid or liquid dispersion, homogenization, agglomeration, or precipitation can create variability in product stability and manufacturing throughput. To develop and manufacture world class products at competitive costs, scientists and engineers use inline particle size measurements to optimize process conditions and consistently meet product quality specifications, at the bench or in manufacturing. Continue reading

AIChE Annual Meeting 2012

I’m really looking forward to attending the annual American Institute of Chemical Engineers (AIChE) meeting in Pittsburgh, PA this year. It is always a great opportunity to meet excellent scientists working in very diverse areas. As a chemical engineer it is also nice to focus on chemical engineering for a change! – since many of the conferences I attend are chemistry orientated.

It is also great to see so many papers being presented that Continue reading

HANBAT International Workshop on Industrial and Pharmaceutical Crystallization

Crystallization is a complicated process where the final crystal product is a function of thermodynamics as well as kinetic and physical phenomenon. Continue reading

19th International Workshop on Industrial Crystallization – BIWIC 2012

During BIWIC 2012 (19th International Workshop on Industrial Crystallization) in China, I will present a poster – Amalgamated Sugar Experiences with Inline Particle Size, Shape, and Count Characterization:  Real-Time Crystal Nucleation and Growth Rates in an Industrial Semi-batch Crystallizer. Continue reading

Engineering Fine Particle Size Distributions with Inline Particle Size Measurements

Crystal engineering is applied when the crystal size distribution is too large to meet downstream specifications. By designing the crystallization to produce a fine crystal distribution in situ, downstream milling operations are avoided, thus improving the yield, and reducing energy consumption or safety hazards which may arise due to milling. Continue reading

Petrophase 13 – Optimize Particle-Water-Oil Separations in Dark Crude Oil

The 13th International Conference on Petroleum Phase Behavior and Fouling will be held June 10 – 14, 2012 in St. Petersburg Beach, Florida. Continue reading