What is happening in my crystallization?
Did the solids crash out? Did a solvent oil out?
When did the crystals begin to agglomerate?
What is the solubility? Did I seed at the right temperature?
Will the product have the purity and yield we require? Will it filter?
Is the process consistent batch to batch?
Is it easily transferred to our manufacturing facility or Contract Manufacturing Organization?
A crystallization workstation with intuitive process monitoring tools will help you to answer these questions by tracking changes from within the crystallization vessel or pipeline. This video shows how chemists and chemical engineers utilize inline particle size measurement tools in a crystallization workstation to understand, optimize, and transfer a crystallization process.
Chemists and Chemical Engineers from GlaxoSmithKline (GSK), Excella, Astra Zeneca and others utilize process monitoring tools to accelerate process development, optimization, and transfer. Results include:
- Higher yields
- Elimination of a costly process impurity
- Increased monthly throughput
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