Optimization of Highly Reactive Chemistry – Reducing Risks

Highly reactive chemistry is the generic term referring to chemical reactions that pose a challenge due to the potentially hazardous and/or energetic nature of the reactants, intermediates and products that are present during synthesis. Highly reactive chemistries include Grignard, acid chloride, azide, halogenation, and hydrogenation. 

Highly Reactive ChemistryThe guide – Optimization of Highly Reactive Chemistry – provides examples of the safe process scale-up and optimization of highly reactive chemistries and outlines how to:

  • Determine optimal process conditions to deliver high yields of desired product
  • Follow reaction progression while eliminating direct exposure to dangerous reaction materials
  • Prevent runaway reactions or explosions