Metal Catalyzed Transformations have been a key topic in academic research for a number of years, both for their scientific interest, as well as the large number of reactions that have become important to industry.
Some of the major challenges faced by researchers today include the need to accurately determine the start and end point of reactions, as well as gaining sufficient information to fully understand, characterize and optimize chemical reactions. This, combined with the need to complete larger numbers of investigations, with less resource and in shorter time, is leading researchers to look for innovative ways to gain the information they require to complete their work successfully.
In situ Infrared (IR) spectroscopy has been increasingly used in synthetic organic chemistry due to its ability to deliver key pieces of information that enables researchers elucidate the mechanism, kinetics and pathway of many different reactions.
A new white paper on Metal Catalyzed Transformations Using In Situ Spectroscopy highlights examples from academia where in situ IR spectroscopy has been used as an enabling tool to uncover key parameters in each investigation. The authors highlight the context in which in situ IR spectroscopy was used and how this helped researchers answer key questions. Work is from research groups at Emory University, University of Albany (SUNY), University of Buffalo (SUNY), Università di Bari (Italy), Wuhan University (China), and Stockholm University (Sweden).